By combining h-HepOrgs with portal mesenchyme and our previously published cholangiocyte organoids 4,5,6 , we generated patient-specific periportal liver assembloids that retain the histological arrangement, gene expression and cell interactions of periportal liver tissue, with cholangiocytes and mesenchyme embedded in the hepatocyte parenchyma
Zeng Y, Zhang J, Xu M, Chen F, Zi R, Yue J, et al
Thus, genetically determined increased MD-2 level (rs11465996) and TNFRSF1A (TNFR1) expression (rs4149570) and genetically determined decreased TNFAIP3 (A20) expression (rs6927172), IL-1 (rs3804099 and rs4848306), IL-6 (rs3804099 and rs10499563), IL-17 (rs2275913) and IFN- (rs2430561) levels were associated with beneficial response among patients with IBD
The bacterial counts obtained at t=0 were set as 100% survival, and the persistence of pneumococci at later time points was expressed as the percentage of surviving levofloxacin-tolerant cells
G., Braas, D
